Natural Power for Joint and muscles
ApiVENZ™ Relief is natural and innovative combination of New Zealand Bee Venom VENZ™ with nutritional properties of Glucosamine. Glucosamine and bee venom maintain joint mobility function and allow keeping joint mobility in normal.
What is so special about Bee Venom Value
Bee venom is a unique multi-component complex, which contains about 30 biologically active compounds, some of which are practically impossible to get synthesized by chemical methods. The main components are peptides: melittin, apamin, peptide 401, adolapin, and protease inhibitors.
Bee venom has multiple effects on the body: help keep the blood circulation in normal, support physical strength and well being, support to joint mobility, has anti-oxidant effects, support to the immune system.
Bee venom might modify the immune system functions in the body and contribute to the increased production of cortisol. The healing potency of BV in the treatment of arthritis and rheumatism is initiated after stimulating the production of cortisol in the adrenal glands.
In animal studies conducted last year, doctors in South Korea found that melittin, the principal peptide in bee venom, blocks the expression of inflammatory genes that can cause painful tissue swelling in rheumatoid arthritis patients.
Next, researchers tested the anti-inflammatory effects of melittin on human synovial cells of arthritis patients. Synovial cells are those that line the joints, and which are vulnerable to inflammation among arthritis sufferers.
They found the melittin blocked the expression of the genes that cause the inflammation and pain suffered by arthritis patients. The melittin worked in a similar way to a class of drugs called cox-2 inhibitors, which are now used to treat rheumatoid arthritis and reduce inflammation, the scientists wrote.
Used Source: Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds.
Glucosamine is a major component of soft tissues such as cartilage, ligament, tendon, skin etc. Glucosamine is produced in the body from glucose and an amino acid, glutamine. It stimulates the manufacture of the soft tissue, as well as promoting the incorporation of sulfur into the tissue, and is therefore responsible for both the manufacture and proper function of joints and tissue such as ligaments, tendons and cartilage.
Glucosamine has been reported to have the potential to slow the degradation of cartilage and can also help the body repair eroded and damaged cartilage. Glucosamine not only stimulates the production of cartilage but it can also improve joint function and help reduce the pain of those suffering from osteoarthritis. Symptoms such as joint tenderness, pain on standing, pain on walking, joint swelling and spontaneous pain can be reduced.
✔ Stimulates the production of cartilage
✔ Improves joint function and helps to reduce the osteoarthritic pain.
✔ Reduce joint tenderness, pain on standing, pain on walking, joint swelling and spontaneous pain
1. Effects of glucosamine in patients with osteoarthritis of the knee: a systematic review and meta-analysis. Ogata T, et al., Clin Rheumatol. 2018 Apr 30. doi: 10.1007/s10067-018-4106-2
2. Effect of oral glucosamine on joint structure in individuals with chronic knee pain: a randomized, placebo-controlled clinical trial. Kwoh CK et al. Arthritis Rheumatol. 2014 Apr;66(4):930-9. doi: 10.1002/art.38314.
✔ Support the immune system
✔ Helps to keep the blood circulation in normal due to its anticoagulant and antiaggregant properties
✔ Supports joint mobility and muscle strength, provides anti-inflammatory and pain relief effects on the patients with rheumatoid arthritis and chronic muscle pain
Md. Sakib Hossen et al. Molecules 2017, 22, 25; doi:10.3390/molecules22010025
New Zealand bee venom VENZ™, Glucosamine HLC
Start from 0.5 tablets a day. If no allergic reaction, take 1-2 tablets daily
People who have allergic reactions to bee sting should seek medical advice before using this product